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Nesprin-2G tension fine-tunes Wnt/β-catenin signaling

How LINC complexes mediate nuclear mechanotransduction remains unclear. In this issue, Déjardin, Carollo, et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908036) show that the LINC complex protein nesprin-2G is a mechanosensor of epithelial–mesenchymal transitions (EMTs), recruiting α-cat...

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Detalles Bibliográficos
Autores principales: Gottardi, Cara J., Luxton, G.W. Gant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659724/
https://www.ncbi.nlm.nih.gov/pubmed/32966550
http://dx.doi.org/10.1083/jcb.202009042