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Nesprin-2G tension fine-tunes Wnt/β-catenin signaling
How LINC complexes mediate nuclear mechanotransduction remains unclear. In this issue, Déjardin, Carollo, et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908036) show that the LINC complex protein nesprin-2G is a mechanosensor of epithelial–mesenchymal transitions (EMTs), recruiting α-cat...
Autores principales: | Gottardi, Cara J., Luxton, G.W. Gant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659724/ https://www.ncbi.nlm.nih.gov/pubmed/32966550 http://dx.doi.org/10.1083/jcb.202009042 |
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