Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging

Short/dysfunctional telomeres are at the origin of idiopathic pulmonary fibrosis (IPF) in patients mutant for telomere maintenance genes. However, it remains unknown whether physiological aging leads to short telomeres in the lung, thus leading to IPF with aging. Here, we find that physiological agi...

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Detalles Bibliográficos
Autores principales: Piñeiro-Hermida, Sergio, Autilio, Chiara, Martínez, Paula, Bosch, Fátima, Pérez-Gil, Jesús, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659728/
https://www.ncbi.nlm.nih.gov/pubmed/32777016
http://dx.doi.org/10.1083/jcb.202002120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659728/
https://www.ncbi.nlm.nih.gov/pubmed/32777016
http://dx.doi.org/10.1083/jcb.202002120

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