Cargando…

Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels

Progression of epithelial cancers predominantly proceeds by collective invasion of cell groups with coordinated cell–cell junctions and multicellular cytoskeletal activity. Collectively invading breast cancer cells express the gap junction protein connexin-43 (Cx43), yet whether Cx43 regulates colle...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalil, Antoine A., Ilina, Olga, Vasaturo, Angela, Venhuizen, Jan-Hendrik, Vullings, Manon, Venhuizen, Victor, Bilos, Ab, Figdor, Carl G., Span, Paul N., Friedl, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659730/
https://www.ncbi.nlm.nih.gov/pubmed/32777015
http://dx.doi.org/10.1083/jcb.201911120