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Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels
Progression of epithelial cancers predominantly proceeds by collective invasion of cell groups with coordinated cell–cell junctions and multicellular cytoskeletal activity. Collectively invading breast cancer cells express the gap junction protein connexin-43 (Cx43), yet whether Cx43 regulates colle...
Autores principales: | Khalil, Antoine A., Ilina, Olga, Vasaturo, Angela, Venhuizen, Jan-Hendrik, Vullings, Manon, Venhuizen, Victor, Bilos, Ab, Figdor, Carl G., Span, Paul N., Friedl, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659730/ https://www.ncbi.nlm.nih.gov/pubmed/32777015 http://dx.doi.org/10.1083/jcb.201911120 |
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