Cargando…

Molecular Regulation of the Polycomb Repressive-Deubiquitinase

Post-translational modification of histone proteins plays a major role in histone–DNA packaging and ultimately gene expression. Attachment of ubiquitin to the C-terminal tail of histone H2A (H2AK119Ub in mammals) is particularly relevant to the repression of gene transcription, and is removed by the...

Descripción completa

Detalles Bibliográficos
Autores principales: Reddington, Cameron J., Fellner, Matthias, Burgess, Abigail E., Mace, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660087/
https://www.ncbi.nlm.nih.gov/pubmed/33105797
http://dx.doi.org/10.3390/ijms21217837