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Molecular Regulation of the Polycomb Repressive-Deubiquitinase
Post-translational modification of histone proteins plays a major role in histone–DNA packaging and ultimately gene expression. Attachment of ubiquitin to the C-terminal tail of histone H2A (H2AK119Ub in mammals) is particularly relevant to the repression of gene transcription, and is removed by the...
Autores principales: | Reddington, Cameron J., Fellner, Matthias, Burgess, Abigail E., Mace, Peter D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660087/ https://www.ncbi.nlm.nih.gov/pubmed/33105797 http://dx.doi.org/10.3390/ijms21217837 |
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