Role of Post-Translational Modifications of cGAS in Innate Immunity

Cyclic GMP–AMP synthase (cGAS) is the synthase that generates the second messenger cyclic GMP–AMP (cGAMP) upon DNA binding. cGAS was first discovered as the cytosolic DNA sensor that detects DNA exposed in the cytoplasm either from pathogens or cellular damage. Activated cGAS instigates the signalin...

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Detalles Bibliográficos
Autores principales: Wu, Yakun, Li, Shitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660100/
https://www.ncbi.nlm.nih.gov/pubmed/33105828
http://dx.doi.org/10.3390/ijms21217842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660100/
https://www.ncbi.nlm.nih.gov/pubmed/33105828
http://dx.doi.org/10.3390/ijms21217842

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