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Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers

The overexpression of survivin is usually accompanied by an increased resistance of cancer cells to chemotherapeutic agents in addition to cancer aggressiveness. Consequently, survivin is considered as an attractive target to develop new promising anticancer candidates. A series of novel 3-cyanopyri...

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Detalles Bibliográficos
Autores principales: Sabour, Rehab, Harras, Marwa F., Mohamed Al Kamaly, Omkulthom, Altwaijry, Najla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660103/
https://www.ncbi.nlm.nih.gov/pubmed/33105831
http://dx.doi.org/10.3390/molecules25214892