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Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers
The overexpression of survivin is usually accompanied by an increased resistance of cancer cells to chemotherapeutic agents in addition to cancer aggressiveness. Consequently, survivin is considered as an attractive target to develop new promising anticancer candidates. A series of novel 3-cyanopyri...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660103/ https://www.ncbi.nlm.nih.gov/pubmed/33105831 http://dx.doi.org/10.3390/molecules25214892 |