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The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study

BACKGROUND: Body mass index (BMI)-associated loci are used to explore the effects of obesity using Mendelian randomization (MR), but the contribution of individual tissues to risks remains unknown. We aimed to identify tissue-grouped pathways of BMI-associated loci and relate these to cardiometaboli...

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Detalles Bibliográficos
Autores principales: Verkouter, Inge, de Mutsert, Renée, Smit, Roelof A J, Trompet, Stella, Rosendaal, Frits R, van Heemst, Diana, Willems van Dijk, Ko, Noordam, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660142/
https://www.ncbi.nlm.nih.gov/pubmed/32500151
http://dx.doi.org/10.1093/ije/dyaa070