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The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study
BACKGROUND: Body mass index (BMI)-associated loci are used to explore the effects of obesity using Mendelian randomization (MR), but the contribution of individual tissues to risks remains unknown. We aimed to identify tissue-grouped pathways of BMI-associated loci and relate these to cardiometaboli...
Autores principales: | Verkouter, Inge, de Mutsert, Renée, Smit, Roelof A J, Trompet, Stella, Rosendaal, Frits R, van Heemst, Diana, Willems van Dijk, Ko, Noordam, Raymond |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660142/ https://www.ncbi.nlm.nih.gov/pubmed/32500151 http://dx.doi.org/10.1093/ije/dyaa070 |
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