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Empirical comparisons of multiple Mendelian randomization approaches in the presence of assortative mating

BACKGROUND: Mendelian randomization (MR) is widely used to unravel causal relationships in epidemiological studies. Whereas multiple MR methods have been developed to control for bias due to horizontal pleiotropy, their performance in the presence of other sources of bias, like non-random mating, ha...

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Detalles Bibliográficos
Autores principales: Minică, Camelia C, Boomsma, Dorret I, Dolan, Conor V, de Geus, Eco, Neale, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660149/
https://www.ncbi.nlm.nih.gov/pubmed/32155257
http://dx.doi.org/10.1093/ije/dyaa013