From Suppressor T Cells to Regulatory T Cells: How the Journey that Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation

Aryl hydrocarbon receptor (AhR) was identified in the early 1970s as a receptor for the ubiquitous environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin), which is a member of halogenated aromatic hydrocarbons (HAHs). TCDD was found to be highly toxic to the immune system, caus...

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Detalles Bibliográficos
Autores principales: Prasad Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660163/
https://www.ncbi.nlm.nih.gov/pubmed/33105907
http://dx.doi.org/10.3390/ijms21217849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660163/
https://www.ncbi.nlm.nih.gov/pubmed/33105907
http://dx.doi.org/10.3390/ijms21217849

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