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OptimalTTF-1: Enhancing tumor treating fields therapy with skull remodeling surgery. A clinical phase I trial in adult recurrent glioblastoma

BACKGROUND: Preclinical studies suggest that skull remodeling surgery (SR-surgery) increases the dose of tumor treating fields (TTFields) in glioblastoma (GBM) and prevents wasteful current shunting through the skin. SR-surgery introduces minor skull defects to focus the cancer-inhibiting currents t...

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Detalles Bibliográficos
Autores principales: Korshoej, Anders Rosendal, Lukacova, Slavka, Lassen-Ramshad, Yasmin, Rahbek, Christian, Severinsen, Kåre Eg, Guldberg, Trine Lignell, Mikic, Nikola, Jensen, Mette Haldrup, Cortnum, Søren Ole Stigaard, von Oettingen, Gorm, Sørensen, Jens Christian Hedemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660275/
https://www.ncbi.nlm.nih.gov/pubmed/33215088
http://dx.doi.org/10.1093/noajnl/vdaa121