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Elevated CLOCK and BMAL1 Contribute to the Impairment of Aerobic Glycolysis from Astrocytes in Alzheimer’s Disease

Altered glucose metabolism has been implicated in the pathogenesis of Alzheimer’s disease (AD). Aerobic glycolysis from astrocytes is a critical metabolic pathway for brain energy metabolism. Disturbances of circadian rhythm have been associated with AD. While the role of circadian locomotor output...

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Detalles Bibliográficos
Autores principales: Yoo, Ik Dong, Park, Min Woo, Cha, Hyeon Woo, Yoon, Sunmi, Boonpraman, Napissara, Yi, Sun Shin, Moon, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660350/
https://www.ncbi.nlm.nih.gov/pubmed/33114015
http://dx.doi.org/10.3390/ijms21217862