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Elevated CLOCK and BMAL1 Contribute to the Impairment of Aerobic Glycolysis from Astrocytes in Alzheimer’s Disease
Altered glucose metabolism has been implicated in the pathogenesis of Alzheimer’s disease (AD). Aerobic glycolysis from astrocytes is a critical metabolic pathway for brain energy metabolism. Disturbances of circadian rhythm have been associated with AD. While the role of circadian locomotor output...
Autores principales: | Yoo, Ik Dong, Park, Min Woo, Cha, Hyeon Woo, Yoon, Sunmi, Boonpraman, Napissara, Yi, Sun Shin, Moon, Jong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660350/ https://www.ncbi.nlm.nih.gov/pubmed/33114015 http://dx.doi.org/10.3390/ijms21217862 |
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