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New insights into the function of mammalian Argonaute2

Uncovering the mechanisms that recognise a microRNA (miRNA) target is 1 of the biggest challenges because the Ago–miRNA complex is able to overcome different derogations of complementarity when binding targets. However, the recently solved crystallographic structure of Argonaute2 (Ago2) and a high-t...

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Detalles Bibliográficos
Autor principal: Marzec, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660459/
https://www.ncbi.nlm.nih.gov/pubmed/33180792
http://dx.doi.org/10.1371/journal.pgen.1009058