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Identification of tyrosine kinase inhibitors that halt Plasmodium falciparum parasitemia

Although current malaria therapies inhibit pathways encoded in the parasite’s genome, we have looked for anti-malaria drugs that can target an erythrocyte component because development of drug resistance might be suppressed if the parasite cannot mutate the drug’s target. In search for such erythroc...

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Detalles Bibliográficos
Autores principales: Kesely, Kristina, Noomuna, Panae, Vieth, Michal, Hipskind, Philip, Haldar, Kasturi, Pantaleo, Antonella, Turrini, Francesco, Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660480/
https://www.ncbi.nlm.nih.gov/pubmed/33180822
http://dx.doi.org/10.1371/journal.pone.0242372