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c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability

The proto-oncogene Src is ubiquitously expressed and is involved in cellular differentiation. However, the role of Src in embryonic stem (ES) cell osteogenic differentiation is largely unknown. Using the small molecule inhibitor PP2, c-Src specific siRNAs, and tet-inducible lentiviral vectors overex...

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Detalles Bibliográficos
Autores principales: Alvandi, Zahra, Opas, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660501/
https://www.ncbi.nlm.nih.gov/pubmed/33180789
http://dx.doi.org/10.1371/journal.pone.0241646