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Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of the cytotoxic efficacy

This study examines the protective effects of omega‐3 fatty acids (OMG), a frequently used nutritional therapy in cancer patients, against doxorubicin (DOX)‐induced acute cardiorenal toxicity in rats, and evaluates the cytotoxic activity of DOX when used with OMG against breast cancer cell line. Fiv...

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Detalles Bibliográficos
Autores principales: Saleh, Dalia, Abdelbaset, Marawan, Hassan, Azza, Sharaf, Ola, Mahmoud, Sawsan, Hegazy, Rehab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660507/
https://www.ncbi.nlm.nih.gov/pubmed/33180794
http://dx.doi.org/10.1371/journal.pone.0242175