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Topoisomerase activity is linked to altered nucleosome positioning and transcriptional regulation in the fission yeast fbp1 gene

Chromatin structure, including nucleosome positioning, has a fundamental role in transcriptional regulation through influencing protein-DNA interactions. DNA topology is known to influence chromatin structure, and in doing so, can also alter transcription. However, detailed mechanism(s) linking tran...

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Detalles Bibliográficos
Autores principales: Asada, Ryuta, Senmatsu, Satoshi, Montpetit, Ben, Hirota, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660550/
https://www.ncbi.nlm.nih.gov/pubmed/33180846
http://dx.doi.org/10.1371/journal.pone.0242348