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In-situ proliferation contributes to the accumulation of myeloid cells in the spleen during progressive experimental visceral leishmaniasis

Visceral leishmaniasis (VL) is characterized by expansion of myeloid cells in the liver and spleen, which leads to a severe splenomegaly associated with higher risk of mortality. This increased cellularity is thought to be a consequence of recruitment of cells to the viscera. We studied whether the...

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Detalles Bibliográficos
Autores principales: Osorio, E. Yaneth, Medina-Colorado, Audrie A., Travi, Bruno L., Melby, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660562/
https://www.ncbi.nlm.nih.gov/pubmed/33180876
http://dx.doi.org/10.1371/journal.pone.0242337