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In-situ proliferation contributes to the accumulation of myeloid cells in the spleen during progressive experimental visceral leishmaniasis
Visceral leishmaniasis (VL) is characterized by expansion of myeloid cells in the liver and spleen, which leads to a severe splenomegaly associated with higher risk of mortality. This increased cellularity is thought to be a consequence of recruitment of cells to the viscera. We studied whether the...
Autores principales: | Osorio, E. Yaneth, Medina-Colorado, Audrie A., Travi, Bruno L., Melby, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660562/ https://www.ncbi.nlm.nih.gov/pubmed/33180876 http://dx.doi.org/10.1371/journal.pone.0242337 |
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