Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study

The intrinsically disordered protein α-synuclein plays a major role in Parkinson’s disease. The protein can oligomerize resulting in the formation of various aggregated species in neuronal cells, leading to neurodegeneration. The interaction of α-synuclein with biological cell membranes plays an imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Moons, Rani, van der Wekken-de Bruijne, Renate, Maudsley, Stuart, Lemière, Filip, Lambeir, Anne-Marie, Sobott, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660655/
https://www.ncbi.nlm.nih.gov/pubmed/33114222
http://dx.doi.org/10.3390/ijms21217884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660655/
https://www.ncbi.nlm.nih.gov/pubmed/33114222
http://dx.doi.org/10.3390/ijms21217884

Ejemplares similares