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Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study
The intrinsically disordered protein α-synuclein plays a major role in Parkinson’s disease. The protein can oligomerize resulting in the formation of various aggregated species in neuronal cells, leading to neurodegeneration. The interaction of α-synuclein with biological cell membranes plays an imp...
Autores principales: | Moons, Rani, van der Wekken-de Bruijne, Renate, Maudsley, Stuart, Lemière, Filip, Lambeir, Anne-Marie, Sobott, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660655/ https://www.ncbi.nlm.nih.gov/pubmed/33114222 http://dx.doi.org/10.3390/ijms21217884 |
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