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Cisplatin-Induced Giant Cells Formation Is Involved in Chemoresistance of Melanoma Cells

Melanoma is notoriously resistant to current cancer therapy. However, the chemoresistance mechanism of melanoma remains unclear. The present study unveiled that chemotherapy drug cisplatin induced the formation of giant cells, which exhibited enlargement in cell diameter and nucleus in mice and huma...

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Detalles Bibliográficos
Autores principales: Weng, Chien-Hui, Wu, Chieh-Shan, Wu, Jian-Ching, Kung, Mei-Lang, Wu, Ming-Hsiu, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660656/
https://www.ncbi.nlm.nih.gov/pubmed/33114317
http://dx.doi.org/10.3390/ijms21217892