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Monitoring Cannabinoid CB2 -Receptor Mediated cAMP Dynamics by FRET-Based Live Cell Imaging

G-protein coupled cannabinoid CB2 receptor signaling and function is primarily mediated by its inhibitory effect on adenylate cyclase. The visualization and monitoring of agonist dependent dynamic 3′,5′-cyclic adenosine monophosphate (cAMP) signaling at the single cell level is still missing for CB2...

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Detalles Bibliográficos
Autores principales: Mensching, Leonore, Rading, Sebastian, Nikolaev, Viacheslav, Karsak, Meliha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660676/
https://www.ncbi.nlm.nih.gov/pubmed/33114208
http://dx.doi.org/10.3390/ijms21217880