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Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial

BACKGROUND: The cysteine protease legumain is increased in patients with atherosclerosis, but its causal role in atherogenesis and cardiovascular disease is still unclear. The aim of the study was to investigate the association of legumain with clinical outcome in a large cohort of patients with acu...

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Detalles Bibliográficos
Autores principales: Gregersen, Ida, Michelsen, Annika E., Lunde, Ngoc Nguyen, Åkerblom, Axel, Lakic, Tatevik G., Skjelland, Mona, Ryeng Skagen, Karolina, Becker, Richard C., Lindbäck, Johan, Himmelmann, Anders, Solberg, Rigmor, Johansen, Harald T., James, Stefan K., Siegbahn, Agneta, Storey, Robert F., Kontny, Frederic, Aukrust, Pål, Ueland, Thor, Wallentin, Lars, Halvorsen, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660754/
https://www.ncbi.nlm.nih.gov/pubmed/32809893
http://dx.doi.org/10.1161/JAHA.120.016360