Osteoprotegerin Prevents Intracranial Aneurysm Progression by Promoting Collagen Biosynthesis and Vascular Smooth Muscle Cell Proliferation

BACKGROUND: Decreased extracellular matrix formation and few vascular smooth muscle cells (VSMCs) in cerebral vascular walls are the main characteristics of intracranial aneurysm (IA) pathogenesis. Recently, osteoprotegerin was reported to activate collagen biosynthesis and VSMC proliferation via th...

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Detalles Bibliográficos
Autores principales: Miyata, Takeshi, Minami, Manabu, Kataoka, Hiroharu, Hayashi, Kosuke, Ikedo, Taichi, Yang, Tao, Yamamoto, Yu, Yokode, Masayuki, Miyamoto, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660769/
https://www.ncbi.nlm.nih.gov/pubmed/32856519
http://dx.doi.org/10.1161/JAHA.119.015731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660769/
https://www.ncbi.nlm.nih.gov/pubmed/32856519
http://dx.doi.org/10.1161/JAHA.119.015731

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