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First Human Use of RUC‐4: A Nonactivating Second‐Generation Small‐Molecule Platelet Glycoprotein IIb/IIIa (Integrin αIIbβ3) Inhibitor Designed for Subcutaneous Point‐of‐Care Treatment of ST‐Segment–Elevation Myocardial Infarction

BACKGROUND: Despite reductions in door‐to‐balloon times for primary coronary intervention, mortality from ST‐segment–elevation myocardial infarction has plateaued. Early pre–primary coronary intervention treatment of ST‐segment–elevation myocardial infarction with glycoprotein IIb/IIIa inhibitors im...

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Detalles Bibliográficos
Autores principales: Kereiakes, Dean J., Henry, Tim D., DeMaria, Anthony N., Bentur, Ohad, Carlson, Marilyn, Seng Yue, Corinne, Martin, Linda H., Midkiff, Jeff, Mueller, Michele, Meek, Terah, Garza, Deborah, Gibson, C. Michael, Coller, Barry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660780/
https://www.ncbi.nlm.nih.gov/pubmed/32844723
http://dx.doi.org/10.1161/JAHA.120.016552