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Laminin‐221 Enhances Therapeutic Effects of Human‐Induced Pluripotent Stem Cell–Derived 3‐Dimensional Engineered Cardiac Tissue Transplantation in a Rat Ischemic Cardiomyopathy Model

BACKGROUND: Extracellular matrix, especially laminin‐221, may play crucial roles in viability and survival of human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPS‐CMs) after in vivo transplant. Then, we hypothesized laminin‐221 may have an adjuvant effect on therapeutic efficacy by enhan...

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Detalles Bibliográficos
Autores principales: Samura, Takaaki, Miyagawa, Shigeru, Kawamura, Takuji, Fukushima, Satsuki, Yokoyama, Jun‐ya, Takeda, Maki, Harada, Akima, Ohashi, Fumiya, Sato‐Nishiuchi, Ryoko, Toyofuku, Toshihiko, Toda, Koichi, Sekiguchi, Kiyotoshi, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660810/
https://www.ncbi.nlm.nih.gov/pubmed/32783519
http://dx.doi.org/10.1161/JAHA.119.015841