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Laminin‐221 Enhances Therapeutic Effects of Human‐Induced Pluripotent Stem Cell–Derived 3‐Dimensional Engineered Cardiac Tissue Transplantation in a Rat Ischemic Cardiomyopathy Model
BACKGROUND: Extracellular matrix, especially laminin‐221, may play crucial roles in viability and survival of human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPS‐CMs) after in vivo transplant. Then, we hypothesized laminin‐221 may have an adjuvant effect on therapeutic efficacy by enhan...
Autores principales: | Samura, Takaaki, Miyagawa, Shigeru, Kawamura, Takuji, Fukushima, Satsuki, Yokoyama, Jun‐ya, Takeda, Maki, Harada, Akima, Ohashi, Fumiya, Sato‐Nishiuchi, Ryoko, Toyofuku, Toshihiko, Toda, Koichi, Sekiguchi, Kiyotoshi, Sawa, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660810/ https://www.ncbi.nlm.nih.gov/pubmed/32783519 http://dx.doi.org/10.1161/JAHA.119.015841 |
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