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Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F

Respiratory syncytial virus (RSV) is a global public health burden for which no licensed vaccine exists. To aid vaccine development via increased understanding of the protective antibody response to RSV prefusion glycoprotein F (PreF), we performed structural and functional studies using the human n...

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Detalles Bibliográficos
Autores principales: Harshbarger, Wayne, Tian, Sai, Wahome, Newton, Balsaraf, Ankita, Bhattacharya, Deep, Jiang, Desheng, Pandey, Ratnesh, Tungare, Kunal, Friedrich, Kristian, Mehzabeen, Nurjahan, Biancucci, Marco, Chinchilla-Olszar, Diana, Mallett, Corey P., Huang, Ying, Wang, Zihao, Bottomley, Matthew James, Malito, Enrico, Chandramouli, Sumana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660905/
https://www.ncbi.nlm.nih.gov/pubmed/33137810
http://dx.doi.org/10.1371/journal.ppat.1008943