Cargando…
Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F
Respiratory syncytial virus (RSV) is a global public health burden for which no licensed vaccine exists. To aid vaccine development via increased understanding of the protective antibody response to RSV prefusion glycoprotein F (PreF), we performed structural and functional studies using the human n...
Autores principales: | Harshbarger, Wayne, Tian, Sai, Wahome, Newton, Balsaraf, Ankita, Bhattacharya, Deep, Jiang, Desheng, Pandey, Ratnesh, Tungare, Kunal, Friedrich, Kristian, Mehzabeen, Nurjahan, Biancucci, Marco, Chinchilla-Olszar, Diana, Mallett, Corey P., Huang, Ying, Wang, Zihao, Bottomley, Matthew James, Malito, Enrico, Chandramouli, Sumana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660905/ https://www.ncbi.nlm.nih.gov/pubmed/33137810 http://dx.doi.org/10.1371/journal.ppat.1008943 |
Ejemplares similares
-
Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein
por: Harshbarger, Wayne, et al.
Publicado: (2021) -
The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors
por: Andreano, Emanuele, et al.
Publicado: (2021) -
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity
por: Williams, James A., et al.
Publicado: (2023) -
Novel Respiratory Syncytial Virus-Like Particle Vaccine Composed of the Postfusion and Prefusion Conformations of the F Glycoprotein
por: Cimica, Velasco, et al.
Publicado: (2016) -
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state
por: Rossey, Iebe, et al.
Publicado: (2017)