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Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis
In mitosis and meiosis, chromosome segregation is triggered by the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit ubiquitin ligase that targets proteins for degradation, leading to the separation of chromatids. APC/C activation requires phosphorylation of its APC3 and APC1 subunits, w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660922/ https://www.ncbi.nlm.nih.gov/pubmed/33137813 http://dx.doi.org/10.1371/journal.pgen.1009184 |