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TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8(AKT1/SGK1) define separate branches of the stress response mechanisms in fission yeast

The Target of rapamycin (TOR) protein kinase forms part of TOR complex 1 (TORC1) and TOR complex 2 (TORC2), two multi-subunit protein complexes that regulate growth, proliferation, survival and developmental processes by phosphorylation and activation of AGC-family kinases. In the fission yeast, Sch...

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Detalles Bibliográficos
Autores principales: Pataki, Emese, Simhaev, Luba, Engel, Hamutal, Cohen, Adiel, Kupiec, Martin, Weisman, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660925/
https://www.ncbi.nlm.nih.gov/pubmed/33137119
http://dx.doi.org/10.1371/journal.pgen.1009196