Cargando…
TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8(AKT1/SGK1) define separate branches of the stress response mechanisms in fission yeast
The Target of rapamycin (TOR) protein kinase forms part of TOR complex 1 (TORC1) and TOR complex 2 (TORC2), two multi-subunit protein complexes that regulate growth, proliferation, survival and developmental processes by phosphorylation and activation of AGC-family kinases. In the fission yeast, Sch...
Autores principales: | Pataki, Emese, Simhaev, Luba, Engel, Hamutal, Cohen, Adiel, Kupiec, Martin, Weisman, Ronit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660925/ https://www.ncbi.nlm.nih.gov/pubmed/33137119 http://dx.doi.org/10.1371/journal.pgen.1009196 |
Ejemplares similares
-
TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes
por: Cohen, Adiel, et al.
Publicado: (2022) -
TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1
por: Laor, Dana, et al.
Publicado: (2015) -
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex
por: Bar-El, Michal Lisnyansky, et al.
Publicado: (2020) -
PIF1 promotes phytochrome-regulated growth under photoperiodic conditions in Arabidopsis together with PIF3, PIF4, and PIF5
por: Soy, Judit, et al.
Publicado: (2014) -
The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1
por: Xu, Xinyuan, et al.
Publicado: (2019)