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Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data
Orienting the causal relationship between pairs of traits is a fundamental task in scientific research with significant implications in practice, such as in prioritizing molecular targets and modifiable risk factors for developing therapeutic and interventional strategies for complex diseases. A rec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660933/ https://www.ncbi.nlm.nih.gov/pubmed/33137120 http://dx.doi.org/10.1371/journal.pgen.1009105 |