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Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data

Orienting the causal relationship between pairs of traits is a fundamental task in scientific research with significant implications in practice, such as in prioritizing molecular targets and modifiable risk factors for developing therapeutic and interventional strategies for complex diseases. A rec...

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Detalles Bibliográficos
Autores principales:	Xue, Haoran, Pan, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7660933/ https://www.ncbi.nlm.nih.gov/pubmed/33137120 http://dx.doi.org/10.1371/journal.pgen.1009105

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