Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes

Brown adipose tissue is a metabolically beneficial organ capable of dissipating chemical energy into heat, thereby increasing energy expenditure. Here, we identify Dot1l, the only known H3K79 methyltransferase, as an interacting partner of Zc3h10 that transcriptionally activates the Ucp1 promoter an...

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Detalles Bibliográficos
Autores principales: Yi, Danielle, Nguyen, Hai P, Dinh, Jennie, Viscarra, Jose A, Xie, Ying, Lin, Frances, Zhu, Madeleine, Dempersmier, Jon M, Wang, Yuhui, Sul, Hei Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661038/
https://www.ncbi.nlm.nih.gov/pubmed/33107819
http://dx.doi.org/10.7554/eLife.59990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661038/
https://www.ncbi.nlm.nih.gov/pubmed/33107819
http://dx.doi.org/10.7554/eLife.59990

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