Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrils

BACKGROUND: Although several studies demonstrate prion-like properties of Tau fibrils, the effect of size in the seeding capacity of these aggregates is not fully understood. The aim of this study is to characterize Tau seeds by their size and seeding capacity. METHODS: Tau aggregates were isolated...

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Detalles Bibliográficos
Autores principales: Marreiro, André, Van Kolen, Kristof, Sousa, Cristiano, Temmerman, Liesbet, Vasconcelos, Bruno, Crespo-Rodriguez, Rosa, van Weering, Jan R. T., Van Dam, Debby, De Deyn, Peter P., Apetri, Adrian, Schoofs, Liliane, Mercken, Marc H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661158/
https://www.ncbi.nlm.nih.gov/pubmed/33183222
http://dx.doi.org/10.1186/s12860-020-00320-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661158/
https://www.ncbi.nlm.nih.gov/pubmed/33183222
http://dx.doi.org/10.1186/s12860-020-00320-y

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