Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice

Frequently reported neurotoxic sequelae of cancer treatment include cognitive deficits and sensorimotor abnormalities that have long-lasting negative effects on the quality of life of an increasing number of cancer survivors. The underlying mechanisms are not fully understood and there is no effecti...

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Detalles Bibliográficos
Autores principales: Chiang, Angie C. A., Seua, Alexandre V., Singhmar, Pooja, Arroyo, Luis D., Mahalingam, Rajasekaran, Hu, Jian, Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661216/
https://www.ncbi.nlm.nih.gov/pubmed/33183353
http://dx.doi.org/10.1186/s40478-020-01061-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661216/
https://www.ncbi.nlm.nih.gov/pubmed/33183353
http://dx.doi.org/10.1186/s40478-020-01061-x

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