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Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications

Oncolytic virotherapies (OV) based on human adenoviral (HAdV) vectors hold significant promise for the treatment of advanced ovarian cancers where local, intraperitoneal delivery to tumour metastases is feasible, bypassing many complexities associated with intravascular delivery. The efficacy of HAd...

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Detalles Bibliográficos
Autores principales: Hulin-Curtis, Sarah L., Davies, James A., Nestić, Davor, Bates, Emily A., Baker, Alexander T., Cunliffe, Tabitha G., Majhen, Dragomira, Chester, John D., Parker, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661341/
https://www.ncbi.nlm.nih.gov/pubmed/31902944
http://dx.doi.org/10.1038/s41417-019-0156-0