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LncRNA SNHG11 facilitates tumor metastasis by interacting with and stabilizing HIF-1α

Epigenetic alteration is one of the hallmarks of colorectal cancer (CRC). Many driver genes are regulated by DNA methylation in CRC. However, the role of DNA methylation regulating lncRNAs remain elusive. Here, we identify that SNHG11 (small nucleolar RNA host gene 11) is upregulated by promotor hyp...

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Detalles Bibliográficos
Autores principales: Xu, Linguo, Huan, Lin, Guo, Tianan, Wu, Yangjun, Liu, Yanfang, Wang, Qifeng, Huang, Shenglin, Xu, Ye, Liang, Linhui, He, Xianghuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661343/
https://www.ncbi.nlm.nih.gov/pubmed/33060856
http://dx.doi.org/10.1038/s41388-020-01512-8