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Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma

BACKGROUND: CD73–adenosine signaling in the tumor microenvironment is immunosuppressive and may be associated with aggressive renal cell carcinoma (RCC). We investigated the prognostic significance of CD73 protein expression in RCC leveraging nephrectomy samples. We also performed a complementary an...

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Detalles Bibliográficos
Autores principales: Tripathi, Abhishek, Lin, Edwin, Xie, Wanling, Flaifel, Abdallah, Steinharter, John A, Stern Gatof, Emily N, Bouchard, Gabrielle, Fleischer, Justin H, Martinez-Chanza, Nieves, Gray, Connor, Mantia, Charlene, Thompson, Linda, Wei, Xiao X, Giannakis, Marios, McGregor, Bradley A, Choueiri, Toni K, Agarwal, Neeraj, McDermott, David F, Signoretti, Sabina, Harshman, Lauren C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661372/
https://www.ncbi.nlm.nih.gov/pubmed/33177176
http://dx.doi.org/10.1136/jitc-2020-001467