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ICP6 Prevents RIP1 Activation to Hinder Necroptosis Signaling

Necroptosis is a type of programmed necrosis which depends on the activation of receptor-interacting protein kinase 3 (RIP3). Herpes simplex virus type 1 (HSV-1) is known to block necroptosis by the viral protein ICP6 in human cells, but its specific inhibitory mechanism is not fully understood. Her...

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Detalles Bibliográficos
Autores principales: Hu, Hong, Wu, Guoxiang, Shu, Zhaoqian, Yu, Dandan, Nan, Ning, Yuan, Feiyang, Liu, Xiaoyan, Wang, Huayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661466/
https://www.ncbi.nlm.nih.gov/pubmed/33195272
http://dx.doi.org/10.3389/fcell.2020.595253