Endoplasmic reticulum chaperone BiP/GRP78 knockdown leads to autophagy and cell death of arginine vasopressin neurons in mice

The immunoglobulin heavy chain binding protein (BiP), also referred to as 78-kDa glucose-regulated protein (GRP78), is a pivotal endoplasmic reticulum (ER) chaperone which modulates the unfolded protein response under ER stress. Our previous studies showed that BiP is expressed in arginine vasopress...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawaguchi, Yohei, Hagiwara, Daisuke, Miyata, Takashi, Hodai, Yuichi, Kurimoto, Junki, Takagi, Hiroshi, Suga, Hidetaka, Kobayashi, Tomoko, Sugiyama, Mariko, Onoue, Takeshi, Ito, Yoshihiro, Iwama, Shintaro, Banno, Ryoichi, Grinevich, Valery, Arima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661499/
https://www.ncbi.nlm.nih.gov/pubmed/33184425
http://dx.doi.org/10.1038/s41598-020-76839-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661499/
https://www.ncbi.nlm.nih.gov/pubmed/33184425
http://dx.doi.org/10.1038/s41598-020-76839-z

Ejemplares similares