Characterization of Affitin proteolytic digestion in biorelevant media and improvement of their stabilities via protein engineering

Affitins are a novel class of small 7 kDa artificial proteins which can be used as antibody substitutes in therapeutic, diagnostic and biotechnological applications. One challenge for this type of protein agent is their behaviour in the context of oral administration. The digestive system is central...

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Detalles Bibliográficos
Autores principales: Loussouarn, Aurélie, Béhar, Ghislaine, Pecorari, Frédéric, Croyal, Mikael, Renodon-Cornière, Axelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661517/
https://www.ncbi.nlm.nih.gov/pubmed/33184451
http://dx.doi.org/10.1038/s41598-020-76855-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661517/
https://www.ncbi.nlm.nih.gov/pubmed/33184451
http://dx.doi.org/10.1038/s41598-020-76855-z

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