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Characterization of Affitin proteolytic digestion in biorelevant media and improvement of their stabilities via protein engineering
Affitins are a novel class of small 7 kDa artificial proteins which can be used as antibody substitutes in therapeutic, diagnostic and biotechnological applications. One challenge for this type of protein agent is their behaviour in the context of oral administration. The digestive system is central...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661517/ https://www.ncbi.nlm.nih.gov/pubmed/33184451 http://dx.doi.org/10.1038/s41598-020-76855-z |