EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) nanoparticles as a carrier for the delivery of CCR2− shRNA to atherosclerotic macrophage in vitro

Reducing macrophage recruitment by silencing chemokine (C–C motif) receptor 2 (CCR2) expression is a promising therapeutic approach against atherosclerosis. However the transfection of macrophages with siRNA is often technically challenging. EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) (PLGA)...

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Detalles Bibliográficos
Autores principales: Wu, Zhilin, Chen, Chen, Luo, Jiajia, Davis, Jacques R. J., Zhang, Bo, Tang, Liang, Shi, Wei, Liao, Danying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661524/
https://www.ncbi.nlm.nih.gov/pubmed/33184330
http://dx.doi.org/10.1038/s41598-020-76416-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661524/
https://www.ncbi.nlm.nih.gov/pubmed/33184330
http://dx.doi.org/10.1038/s41598-020-76416-4

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